Hydrochloric Acid → HCID 21073887, compound

Participants

Reaction Steps

7-{5-[4-(5,6,7,8-Tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-pent-1-enyl}-3,4-dihydro-1H-[1,8]naphthyridin-2-one (0.225 g, 0.523 mmol) was hydrogenated using Ra—Ni (0.25 g) in THF for 16 hours. The reaction was filtered and concentrated to give a foam. This was dissolved in Et2O and 1M HCl in Et2O (1 equiv) was added. The precipitate was filtered and dried to give the title compound as a white solid (0.157 g, 70%). MS: APCI: M+1: 433.4 (Exact Mass: 432.29).

Provenance & Evidence