Ethyl Acetate → HCID 21073445, compound

Participants

Reaction Steps

6-{5-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-pent-1-enyl}-4H-pyrido[3,2-b][1,4]oxazin-3-one (0.774 g, 1.73 mmol) was hydrogenated using Ra—Ni (0.25 g) in THF for 16 hours. The reaction was filtered and concentrated to give an oil. Ethyl acetate was added and the product crashed out. The precipitate was filtered and dried to give the title compound as a white solid (0.645 g, 83%). MS: APCI: M+1: 449.1 (Exact Mass: 448.14).

Provenance & Evidence