Ethyl Acetate → HCID 21073871, compound

Participants

Reaction Steps

7-{5-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-pent-1-enyl}-3,4-dihydro-1H-[1,6]naphthyridin-2-one (0.417 g, 0.937 mmol) was hydrogenated using Ra—Ni (0.25 g) in THF for 2 hours. The reaction was filtered and concentrated to give a white solid. EtOAc was added and the product crashed out. The precipitate was filtered and dried to give the title compound as a white solid (0.391 g, 93%). MS: APCI: M+1: 447.2 (Exact Mass: 446.16).

Provenance & Evidence