HCID 21073153, compound → HCID 21073644, compound

Participants

Reaction Steps

In a manner similar to that of other examples above, 1-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-6-yl)-piperazine hydrochloride (J. Med. Chem. 1988, 31, 1934–1940) was coupled by reductive amination to 4-(7-oxo-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde followed by typical workup and purification to give the intermediate compound. MS: APCI: M+1: 453.6 (Exact Mass: 452.55).

Provenance & Evidence