Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1373649Generated: October 31, 2026

HCID 21073153, compound → HCID 21073643, compound

https://huagongshe.com/reaction/1373649

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21073153HCID 21073153—
Reactant4-(7-Oxo-7,8-dihydro-1,8-naphthyridin-2-yloxy)butanalHCID 21073380—
ProductHCID 21073643HCID 21073643—

Reaction Steps

In a manner similar to that of other examples above, 1-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-6-yl)-piperazine hydrochloride (J. Med. Chem. 1988, 31, 1934–1940) was coupled by reductive amination to 4-(7-oxo-7,8-dihydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde followed by typical workup and purification to give the title compound. MS: APCI: M+1: 451.2 (Exact Mass: 450.23).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07160888B2
Source datasetuspto-grants-2007_01
ORD IDord-fa2173b6ee5b41b997d540f7b302639e
Source noteuspto-grants-2007_01