HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21073153, compound → HCID 21073643, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21073153 | HCID 21073153 | — |
| Reactant | 4-(7-Oxo-7,8-dihydro-1,8-naphthyridin-2-yloxy)butanal | HCID 21073380 | — |
| Product | HCID 21073643 | HCID 21073643 | — |
Reaction Steps
In a manner similar to that of other examples above, 1-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-6-yl)-piperazine hydrochloride (J. Med. Chem. 1988, 31, 1934–1940) was coupled by reductive amination to 4-(7-oxo-7,8-dihydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde followed by typical workup and purification to give the title compound. MS: APCI: M+1: 451.2 (Exact Mass: 450.23).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160888B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-fa2173b6ee5b41b997d540f7b302639e |
| Source note | uspto-grants-2007_01 |