1-Methylhomopiperazine → HCID 21075335, compound

HRID 1373705Notes

Reaction equation

HRID 1373705 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:18][C:19](=[O:31])[C:20]2[CH:25]=[CH:24][C:23](F)=[CH:22][C:21]=2[O:27][CH2:28][CH2:29][OH:30])=[C:6]([CH:17]=1)[C:7]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][N:11]=1)=[O:8].[CH3:32][N:33]1[CH2:39][CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:18][C:19](=[O:31])[C:20]2[CH:25]=[CH:24][C:23]([N:36]3[CH2:37][CH2:38][CH2:39][N:33]([CH3:32])[CH2:34][CH2:35]3)=[CH:22][C:21]=2[O:27][CH2:28][CH2:29][OH:30])=[C:6]([CH:17]=1)[C:7]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][N:11]=1)=[O:8]

Participants

3

Reactant 2

HCID 2283491-MethylhomopiperazineHCID 21075341HCID 21075341, compound

Product 1

HCID 21075335HCID 21075335, compound

Procedure

Prepared from 5-fluoro-2-[4-fluoro-2-(2-hydroxyethoxy)-benzoylamino]-N-(5-chloropyridin-2-yl)-benzamide and 1-methyl-hexahydro-1,4-diazepine to afford 25 mg (24%).

Workup

  1. customto afford 25 mg (24%)

Sources & evidence

ORD record
ord-d9391fcfc3e448d3b27e893c26a2aed3
Source dataset
uspto-grants-2007_01
Patent number
US07163938B2

Reaction notes

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