HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 34257-54-0 | HCID 21075455 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide | HCID 21988164 | 53.7% |
Reaction Steps
2.554 g 66% H2SO4 and 1.454 g 65% nitric acid were mixed at 0° C. 2.395 g 2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide were added in portions at 0° C. After stirring for 30 min. the mixture was diluted with water and the product isolated by filtration. Chromatography on silica yielded 1.6 g of the title compound and 0.37 g 0.58 g of the 8-nitro isomer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07163941B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-63c2cdc6199547ec9023321a689f50c2 |
| Source note | uspto-grants-2007_01 |