6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide → 6-Amino-2,3-dihydro-1,4

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Reaction Steps

0.917 g 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide (from g)) were hydrogenated in a mixture of 20 ml THF and 20 ml MeOH with 0.90 g 5% Pd—C at atmospheric hydrogen pressure for 90 min. at room temperature. The catalyst was filtered off, the filtrate evaporated and the residue chromatographed on silica to yield 370 mg of the title compound.

Provenance & Evidence