5-(4-Iodo-3-methylphenyl)-2-methyloxazole-4-carboxylic acid → N-(2-((4-(1,1-Difluoroethyl)oxazol-2-yl)methyl)-2H-1,2,3-triazol-4-yl)-5-(4-iodo-3-methylphenyl)-2-methyloxazole-4-carboxamide

HRID 137373Notes

Reaction equation

HRID 137373 reaction equation
[F:1][C:2]([CH3:3])([F:4])[c:5]1[n:6][c:7]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH2:16])[n:15]2)[o:8][cH:9]1.[I:17][c:18]1[c:19]([CH3:33])[cH:20][c:21](-[c:24]2[c:25]([C:30](=[O:31])[OH:32])[n:26][c:27]([CH3:29])[o:28]2)[cH:22][cH:23]1>>[F:1][C:2]([CH3:3])([F:4])[c:5]1[n:6][c:7]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH:16][C:30]([c:25]3[c:24](-[c:21]4[cH:20][c:19]([CH3:33])[c:18]([I:17])[cH:23][cH:22]4)[o:28][c:27]([CH3:29])[n:26]3)=[O:31])[n:15]2)[o:8][cH:9]1

Participants

3

Reactant 2

HCID 671278685-(4-Iodo-3-methylphenyl)-2-methyloxazole-4-carboxylic acidHCID 671278932-[4-(1,1-Difluoro-ethyl)-oxazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine

Product 1

HCID 67288310N-(2-((4-(1,1-Difluoroethyl)oxazol-2-yl)methyl)-2H-1,2,3-triazol-4-yl)-5-(4-iodo-3-methylphenyl)-2-methyloxazole-4-carboxamide

Sources & evidence

ORD record
ord-bb9c13f7c05c467aa690710624552c53
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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