Potassium Carbonate → HCID 69764339, compound

Participants

Reaction Steps

A mixture of Example 84A (0.69 g, 2.34 mmol), 2-(2-bromoethoxy)tetrahydro-2H-pyran (1.41 mL, 9.34 mmol) and K2CO3 (1.61 g, 11.68 mmol) in acetone (20 mL) was refluxed overnight and cooled. The solution was filtered, dried with silica gel powder (10 g). 20% Ethyl acetate in hexanes (1 L) and 30% ethyl acetate in hexanes (1 L) were used to run flash chromatography. The title compound was obtained (265.3 mg, 27%). MS (APCI) m/z 424 (M+H)+.

Provenance & Evidence