Pyrrolidine → HCID 69449302, compound

Participants

Reaction Steps

In a similar manner as described in Example 1, from 1-[7-chloro-2-(4-fluorophenyl)-pyrazolo[1,5-α]pyridin-3-yl]ethanone (0.30 g, 1.0 mmol) and pyrrolidine (0.43 mL, 5.2 mmol), 1-[2-(4-fluorophenyl)-7-(1-pyrrolidinyl)pyrazolo[1,5-α]pyridin-3-yl]ethanone (0.30 g, 91%) was obtained as a yellow solid. 1H NMR (CDCl3): δ 7.78 (d, 1H), 7.56 (m, 2H), 7.36 (t, 1H), 7.13 (t, 2H), 6.16 (d, 1H), 3.72 (m, 4H), 2.11 (s, 3H), 1.99 (m, 4H); MS m/z 324 (M+1).

Provenance & Evidence