m-Chloroperbenzoic acid → HCID 21075785, compound

Participants

Reaction Steps

A solution of N-(2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)isopropylamine (334 mg, 1.18 mmol) in 10 mL of CH2Cl2 was treated with 3-chloroperoxybenzoic acid (MCPBA) (77% max., 334 mg, 1.45 mmol). After stirring for 3 h, the reaction was quenched with saturated NaHCO3 solution and extracted into CH2Cl2. The organic portion was washed with saturated NaHCO3 solution, H2O and brine. The organic portion was dried over Na2SO4, filtered and concentrated to give N-(2-butyl-5-oxido-1H-imidazo[4,5-c]quinolin-1-yl)isopropylamine (338 mg) as a light brown solid.

Provenance & Evidence