HuagongsheHuagongshe Chemistry Print Report · For research reference only
Syringaldehyde → Ethyl-alpha-acetyl-3,5-dimethoxy-4-hydroxy-cinnamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Syringaldehyde | HCID 8655 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Piperidin-1-yl-acetic acid | HCID 201097 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Ethyl-alpha-acetyl-3,5-dimethoxy-4-hydroxy-cinnamate | HCID 54431732 | — |
Reaction Steps
Condensation of 3,5-Dimethoxy-4-hydroxy benzaldehyde (syringaldehyde) with ethyl acetoacetate in the presence of piperidine-acetic acid and benzene as the reaction medium at reflux temperature yields the title product. The reaction takes about 3.5 hours for completion.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07166273B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-8fcc5cfecdda4a91b87bd31d63eb0661 |
| Source note | uspto-grants-2007_01 |