3-(Dimethylamino)propyl chloride hydrochloride → HCID 10363581, compound

HRID 1374520Notes

Reaction equation

HRID 1374520 reaction equation
Cl.CN(C)CCCCl.[Cl:9][C:10]1[CH:43]=[CH:42][C:13]2[S:14][C:15]3[CH:41]=[CH:40][CH:39]=[CH:38][C:16]=3[C:17]3[N:18](COCC[Si](C)(C)C)[C:19]([CH2:22][O:23][CH2:24][CH2:25][CH2:26][N:27]([CH3:29])[CH3:28])=[N:20][C:21]=3[C:12]=2[CH:11]=1>>[Cl:9][C:10]1[CH:43]=[CH:42][C:13]2[S:14][C:15]3[CH:41]=[CH:40][CH:39]=[CH:38][C:16]=3[C:17]3[NH:18][C:19]([CH2:22][O:23][CH2:24][CH2:25][CH2:26][N:27]([CH3:28])[CH3:29])=[N:20][C:21]=3[C:12]=2[CH:11]=1

Participants

3

Reactant 2

HCID 943083-(Dimethylamino)propyl chloride hydrochlorideHCID 10098496HCID 10098496, compound

Product 1

HCID 10363581HCID 10363581, compound

Procedure

By a reaction of alcohol 34 (0.34 mmole) and 3-dimethylaminopropylchloride-hydrochloride (4.8 mmole), {3-[5-chloro-1-(2-trimethylsilyl-ethoxymethyl)-1H-8-thia-1,3-diaza-dibenzo[e,h]azulene-2-ylmethoxy]-propyl}-dimethyl-amine in the form of an oily product was obtained;

Workup

  1. customwas obtained

Sources & evidence

ORD record
ord-7f792982863f413aad858e646a467471
Source dataset
uspto-grants-2007_01
Patent number
US07166583B2

Reaction notes

Loading…