HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl malonate → HCID 16638931, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl malonate | HCID 7943 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 16638804 | HCID 16638804 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 16638931 | HCID 16638931 | — |
Reaction Steps
1-Bromo-2-(2-iodoethyl)-4-(1-methylethoxy)-5-methoxybenzene (18.0 g, 45.1 mmol), potassium carbonate (32.0 g, 321 mmol, anhydrous, freshly ground) and malonic acid dimethyl ester (50.0 g, 378 mmol) are stirred in absolute DMF (200 ml) for 12 hours at 80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07166588B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-d51220d6eb7747be914d8266075ad348 |
| Source note | uspto-grants-2007_01 |