Phenyl isocyanate → HCID 44433881, compound

HRID 1374565Notes

Reaction equation

HRID 1374565 reaction equation
[C:1]1([N:7]=[C:8]=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH:10][C@@H:11]([CH3:32])[C:12]([NH:14][CH:15]1[C:21](=[O:22])[N:20]([CH3:23])[C:19]2[CH:24]=[CH:25][CH:26]=[CH:27][C:18]=2[C:17]2[CH:28]=[CH:29][CH:30]=[CH:31][C:16]1=2)=[O:13]>>[CH3:23][N:20]1[C:21](=[O:22])[CH:15]([NH:14][C:12]([C@@H:11]([O:10][C:8](=[O:9])[NH:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH3:32])=[O:13])[C:16]2[CH:31]=[CH:30][CH:29]=[CH:28][C:17]=2[C:18]2[CH:27]=[CH:26][CH:25]=[CH:24][C:19]1=2

Participants

3

Reactant 2

HCID 7672Phenyl isocyanateHCID 69507835HCID 69507835, compound

Product 1

HCID 44433881HCID 44433881, compound

Procedure

The title compound, MS: m/e=430.3 (M+H+), was prepared in analogy to example 1 from phenylisocyanate and (S)-2-hydroxy-N-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-propionamide.

Sources & evidence

ORD record
ord-d1062ea8f9ce4d46bdcf42d175582e32
Source dataset
uspto-grants-2007_01
Patent number
US07166587B2

Reaction notes

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