Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | HCID 178511566 | HCID 178511566 | — |
| Product | HCID 178501209 | HCID 178501209 | — |
Reaction Steps
5 cm3 of sulfonyl chloride are added dropwise to 50 cm3 of methanol cooled to −10° C. After stirring for 10 minutes at 20° C., 5.0 g of cis-4-aminocyclohexane-1-carboxylic acid are slowly added in fractions. After stirring for 2 hours at ,20° C., the reaction mixture is concentrated to dryness under reduced pressure (2.7 kPa) at 20° C., to give 7.5 g of methyl cis-4-aminocyclohexane-1-carboxylate hydrochloride, in the form of a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07166594B2 |
|---|
| Source dataset | uspto-grants-2007_01 |
|---|
| ORD ID | ord-ee5a4129c26c418eb312d65c6109a6c0 |
|---|
| Source note | uspto-grants-2007_01 |
|---|
