Triethylamine → HCID 131723194, compound

Participants

Reaction Conditions

Reaction Steps

A solution of thevetose (50 A) (1.5 g), cymarose (40) (1.3 g), and molecular sieves 4Å in dichloromethane is stirred at room temperature for 1 hour. The reaction mixture is cooled to −15° C., and tin (II) chloride (0.8 g) and silver trifluoromethanesulphonate (1.1 g) are added. The mixture is stirred at −15° C. for 16 hours, after which triethylamine (0.5 ml) is added. The reaction product is filtered and the dichloromethane is evaporated. The dissaccharide (53) is purified by silica gel column chromatography eluting with ethyl acetate:hexane (2:8), yield 15%.

Provenance & Evidence