Chlorotrimethylsilane → HCID 86599797, compound

HRID 1374797Notes

Reaction equation

HRID 1374797 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]([OH:20])=[O:19])[CH:16]=3)[NH:11][C:10]=2[CH3:21])=[CH:4][CH:3]=1.[CH3:22][Si](Cl)(C)C>CO>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]([O:20][CH3:22])=[O:19])[CH:16]=3)[NH:11][C:10]=2[CH3:21])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 6397ChlorotrimethylsilaneHCID 21077833HCID 21077833, compound

Product 1

HCID 86599797HCID 86599797, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution/suspension of the product from part (i) (1 g) in methanol (50 ml) was added trimethylsilylchloride (12.6 ml). After stirring at room temperture overnight the mixture was concentrated in vacuo to give sub-title compound in quantitative yield.

Workup

  1. concentrationwas concentrated in vacuo

Sources & evidence

ORD record
ord-0acaa362b6954244bc24e92122dd0384
Source dataset
uspto-grants-2007_01
Patent number
US07166607B2

Reaction notes

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