tert-Butyl bromoacetate → HCID 86599798, compound

HRID 1374798Notes

Reaction equation

HRID 1374798 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]([O:20][CH3:21])=[O:19])[CH:16]=3)[NH:11][C:10]=2[CH3:22])=[CH:4][CH:3]=1.[C:23]([O:27][C:28](=[O:31])[CH2:29]Br)([CH3:26])([CH3:25])[CH3:24]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]([O:20][CH3:21])=[O:19])[CH:16]=3)[N:11]([CH2:29][C:28]([O:27][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:31])[C:10]=2[CH3:22])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 79177tert-Butyl bromoacetateHCID 86599797HCID 86599797, compound2×

Product 1

HCID 86599798HCID 86599798, compound

Procedure

The sub-title compound was prepared by the method of example 11 part (ii) using the product of part (ii) and t-butylbromoacetate. The product was purified using flash column chromatography (14% EtOAc/hexane as eluent).

Workup

  1. customThe product was purified

Sources & evidence

ORD record
ord-b4c0a57a35704d0c97f63b0eb08f2c5e
Source dataset
uspto-grants-2007_01
Patent number
US07166607B2

Reaction notes

Loading…