HCID 11740214, compound → HCID 10022316, compound

HRID 1374800Notes

Reaction equation

HRID 1374800 reaction equation
ClC1C=CC(S[C:9]2C3C(=CC=C(C(OC)=O)C=3)[NH:11][C:10]=2C)=CC=1.C([C:26]1[CH:27]=[C:28]2[C:32](=[CH:33][CH:34]=1)[N:31]([CH2:35][C:36]([OH:38])=[O:37])[C:30]([CH3:39])=[C:29]2[S:40][C:41]1[CH:46]=[CH:45][C:44]([Cl:47])=[CH:43][CH:42]=1)(O)=O>>[Cl:47][C:44]1[CH:43]=[CH:42][C:41]([S:40][C:29]2[C:28]3[C:32](=[CH:33][CH:34]=[CH:26][C:27]=3[NH:11][CH2:10][CH3:9])[N:31]([CH2:35][C:36]([OH:38])=[O:37])[C:30]=2[CH3:39])=[CH:46][CH:45]=1

Participants

3

Reactant 2

HCID 11740214HCID 11740214, compoundHCID 86599797HCID 86599797, compound

Product 1

HCID 10022316HCID 10022316, compound

Procedure

The compound was prepared using the method of example 55 part (ii) using the by product from example 2 part (i). Purification by reverse phase preparative HPLC.

Workup

  1. customThe compound was prepared
  2. customPurification by reverse phase preparative HPLC

Sources & evidence

ORD record
ord-47d237ba87bf467198d77f8e03dc3e92
Source dataset
uspto-grants-2007_01
Patent number
US07166607B2

Reaction notes

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