HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86603578, compound → HCID 11162908, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86603578 | HCID 86603578 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 11162908 | HCID 11162908 | 38% |
Reaction Steps
A mixture consisting of N-[(R)-2-(5-benzyl-[1,3,4]oxadiazol-2-yl)-heptyl]-N-benzyloxy formamide (108 mg crude) with 10% palladium on carbon was stirred under an atmosphere of hydrogen for 5.5 h. The mixture was filtered and solvent removed in vacuo. Purification by preparative HPLC provided the title compound (30 mg, 38% for two steps). Mass spectrum ES+: 318 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07166624B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-b022e8a78dce4294a83b38476f9bd5e7 |
| Source note | uspto-grants-2007_01 |