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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1374910Generated: November 1, 2026

2-(5-Chloro-3-pyridyloxy)butyric acid → 2-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide

https://huagongshe.com/reaction/1374910

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Chloro-3-pyridyloxy)butyric acidHCID 21078378—
Reactant5-Amino-2-methoxy-5-methylhex-3-yne hydrochlorideHCID 21078425—
Product2-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramideHCID 21078384—

Reaction Steps

5-Amino-2-methoxy-5-methylhex-3-yne hydrochloride was reacted with 2-(5-chloro-3-pyridyloxy)butyric acid in a similar procedure to Example 1, Stage 3 to give 2-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide as a yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07166621B2
Source datasetuspto-grants-2007_01
ORD IDord-fca56104198a4b5b96d1612f2210f170
Source noteuspto-grants-2007_01