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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1374919Generated: November 1, 2026

3-Hydroxy-5-chloropyridine → (5-chloro-3-pyridyloxy)-N-(1-methoxy-4-methylpent-2-yn-4-yl)-3-methoxypropionamide

https://huagongshe.com/reaction/1374919

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-5-chloropyridineHCID 582305—
ReactantHCID 21078403HCID 21078403—
Product(5-chloro-3-pyridyloxy)-N-(1-methoxy-4-methylpent-2-yn-4-yl)-3-methoxypropionamideHCID 21078428—

Reaction Steps

2-Bromo-N-(1-methoxy-4-methylpent-2-yn-4-yl)-3-methoxypropionamide was reacted with 3-chloro-5-hydroxypyridine in a similar procedure to Example 10, Stage 2 to give the required product as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07166621B2
Source datasetuspto-grants-2007_01
ORD IDord-94aa0232976e4a4db47e4205d36f00bb
Source noteuspto-grants-2007_01