Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 4,5-Dimethylthiazole | HCID 62510 | — |
| Product | HCID 9899451 | HCID 9899451 | — |
Reaction Steps
A mixture of 4,5-dimethylthiazole and bromoacetonitrile were heated with stirring at 95° C. for 1 hour. The product precipitated from the mixture within 30 minutes. After cooling to room temperature, the product a solution of 30% v/v of diethyl ether: CH3CN (10 mL) was added with stirring. The crude product was recovered by filtration, and recrystallized from a mixture of EtOH and CH3CN to yield 2.136 g of 3-(cyanomethyl)-4,5-dimethylthiazolium bromide as needles: mp 184–186° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07166625B2 |
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| Source dataset | uspto-grants-2007_01 |
|---|
| ORD ID | ord-9618cc517386471ab055970e12495dd2 |
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| Source note | uspto-grants-2007_01 |
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