Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | 3,4-Dichloroaniline | HCID 7257 | — |
| Product | 3-(3,4-dichloroanilino)indol-2-one | HCID 135544243 | 95.2% |
Reaction Steps
A mixture of 1H-indole-2,3-dione (10.3 g, 70 mmol), 3,4-dichloroaniline (17.0 g, 70 mmol) was heated at 75° C. for 2 hours in a tightly sealed round bottom flask under argon and cooled to room temperature. The solid was recrystallized from CH2Cl2, giving the desired product (19.4 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07166635B2 |
|---|
| Source dataset | uspto-grants-2007_01 |
|---|
| ORD ID | ord-e37ba73ffbfb4eeb8a91406ce9ef5858 |
|---|
| Source note | uspto-grants-2007_01 |
|---|
