Chloride → HCID 22022460, compound

Participants

Reaction Steps

A solution of N-(3-methoxyphenyl)-N-phenylamine (1.14 g, 5.72 in ether (3 mL) was added to a solution of oxylyl chloride (728 g, 5.75 mmol)and heated at reflux for 1 hour. The resulting mixture was cooled to room temperature, concentrated to dryness, and redissolved in nitrobenzene (35 mL). The solution was added to a solution of AlCl3 in nitrobenzene (0.762 g, 5.72 mmol), and the resulting mixture was heated at 70° C. for 16 hours. The crude product was concentrated in vacuo and purified by column chromatography [eluent: EtOAc/hexane (1:1)], giving the desired product (60 mg, 50%).

Provenance & Evidence