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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1375084Generated: October 26, 2026

Water → Actarit

https://huagongshe.com/reaction/1375084

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantAcetic AnhydrideHCID 7918—
Reactant4-Aminophenylacetic acidHCID 14533—
SolventAcetic AcidHCID 176—
ProductActaritHCID 2018—

Reaction Steps

A mixture of (4-amino-phenyl)-acetic acid (25 g) in acetic acid (200 mL) was treated with acetic anhydride (31.3 mL). The mixture was heated on a steam bath for 4 hours, then cooled, then treated with water (20 mL) and then evaporated. The residue was dried under vacuum to give the title compound (30.4 g) as a beige coloured solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07166616B2
Source datasetuspto-grants-2007_01
ORD IDord-fbc6011db07f4599837d3cc911c5dfb4
Source noteuspto-grants-2007_01