HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → 4-Isobutyl-3-nitro quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | Triethanolamine | HCID 7618 | — |
| Reactant | 4-Chloro-3-nitroquinoline | HCID 11275808 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Isobutyl-3-nitro quinoline | HCID 22590498 | — |
Reaction Steps
4-chloro-3-nitro-quinoline is reacted with isobutyl amine in the presence of triethanolamine (TEA) at between −10 and +15° C. in toluene, while excluding moisture. After washing and phase separation, the organic solution is ready for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07166721B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-141466dddea84eadb5617a749c199086 |
| Source note | uspto-grants-2007_01 |