HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Tryptophan → 4-Bromo-N-[(1S)-1-cyclohexyl-2-hydroxyethyl]benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Tryptophan | HCID 6305 | — |
| Reactant | p-Bromobenzenesulfonyl chloride | HCID 7396 | — |
| Reactant | D-Methionine | HCID 84815 | — |
| Reactant | D-p-hydroxyphenylglycine | HCID 89853 | — |
| Reactant | (alphaS)-alpha-Aminocyclohexaneacetic acid | HCID 736848 | — |
| Product | 4-Bromo-N-[(1S)-1-cyclohexyl-2-hydroxyethyl]benzenesulfonamide | HCID 9975874 | — |
Reaction Steps
The following compounds (Examples 16–19, Table 3) were prepared using 4-bromobenzensulfonyl chloride with L-cyclohexylglycine, D-4-hydroxyphenylglycine, D-methionine, and L-tryptophan and following the procedure outlined in Example 16.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07166622B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-0507b1a70948434eb1199e38438ef8e8 |
| Source note | uspto-grants-2007_01 |