Methyl iodide → HCID 21078809, compound

HRID 1375238Notes

Reaction equation

[CH:1]1([CH2:4][NH:5][C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3[CH:19]=[C:18]([C:20]4[O:21][C:22]([CH3:25])=[N:23][N:24]=4)[CH:17]=[CH:16][C:15]=3[CH3:26])=[CH:10][CH:9]=2)=[O:7])[CH2:3][CH2:2]1.I[CH3:28]>>[CH:1]1([CH2:4][N:5]([CH3:28])[C:6]([C:8]2[CH:9]=[CH:10][C:11]([C:14]3[CH:19]=[C:18]([C:20]4[O:21][C:22]([CH3:25])=[N:23][N:24]=4)[CH:17]=[CH:16][C:15]=3[CH3:26])=[CH:12][CH:13]=2)=[O:7])[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 21078798HCID 21078798, compound

Product 1

HCID 21078809HCID 21078809, compound

Procedure

N-(Cyclopropylmethyl)-N-methyl-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from N-(cyclopropylmethyl)-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide and iodomethane using method H.

Sources & evidence

ORD record: ord-665d1b347eb948a5a6f15ae8813459ec
Source dataset: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07166623B2

Reaction notes

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