4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid → HCID 21078783, compound

HRID 1375244Notes

Reaction equation

HRID 1375244 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[NH2:23][CH2:24][C:25]([NH:27][C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([O:36][CH3:37])[CH:29]=1)=[O:26]>>[CH3:37][O:36][C:30]1[CH:29]=[C:28]([NH:27][C:25](=[O:26])[CH2:24][NH:23][C:20]([C:17]2[CH:16]=[CH:15][C:14]([C:3]3[CH:4]=[C:5]([C:8]4[O:9][C:10]([CH3:13])=[N:11][N:12]=4)[CH:6]=[CH:7][C:2]=3[CH3:1])=[CH:19][CH:18]=2)=[O:21])[CH:33]=[CH:32][C:31]=1[O:34][CH3:35]

Participants

3

Reactant 2

HCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic AcidHCID 20391581HCID 20391581, compound

Product 1

HCID 21078783HCID 21078783, compound

Procedure

N-[2-(3,4-Dimethoxyphenylamino)-2-oxoethyl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2 -yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4 oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 2-amino-N-(3,4-dimethoxyphenyl)acetamide using method I.

Sources & evidence

ORD record
ord-5a7c99d83e1845089708984d58953740
Source dataset
uspto-grants-2007_01
Patent number
US07166623B2

Reaction notes

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