HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → HCID 52949450, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | 2-chloro-N-cyclopentyl-5-nitropyrimidin-4-amine | HCID 7147253 | — |
| Solvent | Ammonia | HCID 222 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 52949450 | HCID 52949450 | 45.5% |
Reaction Steps
A mixture of 0.64 g (3 mmol) of 2-chloro-4-(cyclopentylamino)-5-nitropyrimidine and 0.62 g (6.6 mmol) of 4-aminopyridine in 5 mL of DMSO is stirred at room temperature for 15 minutes. The solution is diluted with water and basified with aqueous ammonia to give 0.41 g (44%) of the title compound: mp (EtOH) 219–221° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169778B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-e0b021c9769a4da88b4818a21c5f5afd |
| Source note | uspto-grants-2007_01 |