Methanol → Benzoic acid, 3,5-dichloro-4-methyl-, methyl ester

HRID 13754Notes

Reaction equation

HRID 13754 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([Cl:12])[C:10]=1[CH3:11])[C:5]([OH:7])=[O:6].[CH3:13]O>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([Cl:12])[C:10]=1[CH3:11])[C:5]([O:7][CH3:13])=[O:6]

Participants

3

Reactant 2

HCID 887MethanolHCID 185332343,5-Dichloro-4-methylbenzoic acid

Product 1

HCID 10130655Benzoic acid, 3,5-dichloro-4-methyl-, methyl ester

Procedure

This compound was prepared in the same manner as in Reference Example 1 (step 1), except that 3,5-dichloro-4-methylbenzoic acid (Japanese Unexamined Patent Publication (Kokai) No. 6-192196) was used and methanol was used as the solvent, and that the crude product was purified by silica gel column chromatography.

Workup

  1. customthat the crude product was purified by silica gel column chromatography

Sources & evidence

ORD record
ord-e51b2b92542745ac848a958d9fc03db1
Source dataset
uspto-grants-2010_06
Patent number
US07728131B2

Reaction notes

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