Benzoyl Peroxide → HCID 17961860, compound

HRID 1375531Notes

Reaction equation

HRID 1375531 reaction equation
[CH3:1][C:2]([CH3:26])([CH3:25])[C:3]([O:5][C:6]1[C:11](=[O:12])[N:10]([CH3:13])[C:9]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)=[N:8][C:7]=1[C:21]([O:23][CH3:24])=[O:22])=[O:4].[Br:27]N1C(=O)CCC1=O.C(Cl)(Cl)(Cl)Cl.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>>[Br:27][CH2:20][C:17]1[CH:18]=[CH:19][C:14]([C:9]2[N:10]([CH3:13])[C:11](=[O:12])[C:6]([O:5][C:3](=[O:4])[C:2]([CH3:26])([CH3:25])[CH3:1])=[C:7]([C:21]([O:23][CH3:24])=[O:22])[N:8]=2)=[CH:15][CH:16]=1

Participants

4

Reactant 3

HCID 7187Benzoyl PeroxideHCID 17961704HCID 17961704, compoundHCID 17961771HCID 17961771, compound

Product 1

HCID 17961860HCID 17961860, compound

Procedure

To a vigorously boiling solution of methyl 5-[(2,2-dimethylpropanoyl)oxy]-1-methyl-2-(4-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxylate in carbon tetrachloride N-bromosuccinimide (1 eq.) and benzoyl peroxide (0.05 eq.) were added as dry powders. After 4 hr the mixture was allowed to reach room temperature and the precipitated succinimide was filtered off. The filtrate was evaporated under vacuum and the solid residue was used as such.

Workup

  1. customas dry powders
  2. customto reach room temperature
  3. filtrationthe precipitated succinimide was filtered off
  4. customThe filtrate was evaporated under vacuum

Sources & evidence

ORD record
ord-f7a0181cd2494f85b1cfafbb2712fbde
Source dataset
uspto-grants-2007_01
Patent number
US07169780B2

Reaction notes

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