HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl acetylenedicarboxylate → HCID 86609164, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl acetylenedicarboxylate | HCID 12980 | — |
| Reactant | HCID 86609163 | HCID 86609163 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 86609164 | HCID 86609164 | — |
Reaction Steps
Benzyl-(2S,4S)-2-[amino(hydroxyimino)methyl]-4-fluoropyrrolidine-1-carboxylate in chloroform was treated with dimethylacetylene dicarboxylate for 3 hours at 60° C. The chloroform was then concentrated to give the title compound as a 8:2 mixture of isomers.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169780B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-f6b04d155fc64364a45c3358b1dc2bd1 |
| Source note | uspto-grants-2007_01 |