HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1375615Generated: October 28, 2026
N,N-Dimethylglycine → HCID 11364178, compound
https://huagongshe.com/reaction/1375615
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,N-Dimethylglycine | HCID 673 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate | HCID 151348 | — |
| Reactant | HCID 11397381 | HCID 11397381 | — |
| Solvent | tetrahydrofuran N,N-dimethylformamide | HCID 21974620 | — |
| Product | HCID 11364178 | HCID 11364178 | — |
Reaction Steps
To a mixture of the product obtained from Example 3 (20 mg, 0.047 mmol) in THF/DMF (2.5/1.0 mL) were added DIEA (0.1 mL), N,N-dimethylglycine (50 mg), and BOP reagent (100 mg). The resulting mixture was stirred at 0° C. for 1.5 hr. The solvent was evaporated. HPLC separation (30% to 100% acetonitrile/water) gave the title compound as a white solid. LC-MS found: (M+1)+=507.26.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07169795B2 |
|---|
| Source dataset | uspto-grants-2007_01 |
|---|
| ORD ID | ord-2e7063e3df9e4e398e6674dcfaee110c |
|---|
| Source note | uspto-grants-2007_01 |
|---|
