HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-3-phenylisoxazole-4-carboxylic acid → 5-Methyl-3-phenylisoxazole-4-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-3-phenylisoxazole-4-carboxylic acid | HCID 14343 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | 5-Methyl-3-phenylisoxazole-4-carbonyl chloride | HCID 85624 | — |
Reaction Steps
5-Methyl-3-phenyl-isoxazole-4-carboxylic acid (0.54 g, 2.56 mmol) was treated with SOCl2 (2 mL) at 70° C. for 1 hr. Concentration in vacuum gave a yellow oil which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169798B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-a0fc13a0bde347f79656113132ca5a68 |
| Source note | uspto-grants-2007_01 |