HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1375839Generated: October 29, 2026
4-Fluorophenyl isocyanate → HCID 22667045, compound
https://huagongshe.com/reaction/1375839
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | 2-Chloro-4-((6,7-dimethoxyquinazolin-4-yl)oxy)aniline | HCID 21889899 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 22667045 | HCID 22667045 | 81% |
Reaction Steps
2-Chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]-aniline 50 mg) was dissolved in chloroform (5 ml), and p-fluorophenyl isocyanate (21 μl) was then added to the solution. The mixture was stirred at 60° C. for one hr. The precipitated crystal was collected by filtration and was washed to give 57 mg (yield 81%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07169789B2 |
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| Source dataset | uspto-grants-2007_01 |
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| ORD ID | ord-c885e284710b4af88da4c1302dc5377e |
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| Source note | uspto-grants-2007_01 |
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