HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluorophenyl isocyanate → HCID 22667142, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluorophenyl isocyanate | HCID 593258 | — |
| Reactant | HCID 22667239 | HCID 22667239 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 22667142 | HCID 22667142 | 79% |
Reaction Steps
4-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-3-methylaniline (50 mg) was dissolved in chloroform (3 ml), and 2,4-difluorophenyl isocyanate (23 μl) was then added to the solution. The mixture was heated under reflux overnight. The precipitated crystal was collected by filtration and was washed to give 59 mg (yield 79%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169789B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-9cde0994759841c88ab47db11ce270f7 |
| Source note | uspto-grants-2007_01 |