Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1375853Generated: October 29, 2026

2,4-Difluorophenyl isocyanate → HCID 22667142, compound

https://huagongshe.com/reaction/1375853

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorophenyl isocyanateHCID 593258—
ReactantHCID 22667239HCID 22667239—
SolventChloroformHCID 6212—
ProductHCID 22667142HCID 2266714279%

Reaction Steps

4-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-3-methylaniline (50 mg) was dissolved in chloroform (3 ml), and 2,4-difluorophenyl isocyanate (23 μl) was then added to the solution. The mixture was heated under reflux overnight. The precipitated crystal was collected by filtration and was washed to give 59 mg (yield 79%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07169789B2
Source datasetuspto-grants-2007_01
ORD IDord-9cde0994759841c88ab47db11ce270f7
Source noteuspto-grants-2007_01