HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 69367429, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Benzene, 1-isocyanato-2-methoxy- | HCID 69695 | — |
| Reactant | HCID 22667239 | HCID 22667239 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 69367429 | HCID 69367429 | 55% |
Reaction Steps
4-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-3-methylaniline (50 mg) was dissolved in chloroform (3 ml), and 2-methoxyphenyl isocyanate (26 μl) was then added to the solution. The mixture was heated under reflux overnight. Methanol was added to the reaction solution, and the mixture was purified by HPLC by development with chloroform/methanol to give 41 mg (yield 55%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169789B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-bb6ec1075ab149a1b4421e725299d45e |
| Source note | uspto-grants-2007_01 |