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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1375857Generated: November 1, 2026

2,4-Difluorophenyl isocyanate → HCID 22667079, compound

https://huagongshe.com/reaction/1375857

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorophenyl isocyanateHCID 593258—
ReactantHCID 22667151HCID 22667151—
SolventChloroformHCID 6212—
ProductHCID 22667079HCID 22667079—

Reaction Steps

4-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-2-methylaniline (50 mg) was dissolved in chloroform (3 ml), and 2,4-difluorophenyl isocyanate (23 μl) was then added to the solution. The mixture was heated under reflux overnight. The precipitated crystal was collected by filtration and was washed to quantitatively give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07169789B2
Source datasetuspto-grants-2007_01
ORD IDord-1270759f17e44ee58fa7a91b79fecdaf
Source noteuspto-grants-2007_01