HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1375923Generated: November 1, 2026
4-[2-(4-Bromophenyl)vinyl]-4-(t-butyldimethylsilanyloxymethyl)-2-methyl-4,5-dihydrooxazole → HCID 69430585, compound
https://huagongshe.com/reaction/1375923
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-[2-(4-Bromophenyl)vinyl]-4-(t-butyldimethylsilanyloxymethyl)-2-methyl-4,5-dihydrooxazole | HCID 69427227 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Chlorotris(triphenylphosphine)rhodium(I) | HCID 84599 | — |
| Product | HCID 69430585 | HCID 69430585 | — |
Reaction Steps
4-[2-(4-Bromophenyl)vinyl]-4-(t-butyldimethylsilanyloxymethyl)-2-methyl-4,5-dihydrooxazole (3 mmol) is dissolved in ethanol (15 mL) and hydrogenated at atmospheric pressure in the presence of chlorotris(triphenylphosphine)rhodium(I) (10%). The mixture is stirred at 40° C. for 12 h. After filtration and concentration, the crude product is obtained as colorless oil, which is used directly in the next step without further purification. MS: (ES+): 412.1 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07169817B2 |
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| Source dataset | uspto-grants-2007_01 |
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| ORD ID | ord-55a55965677246899646a33806a3884b |
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| Source note | uspto-grants-2007_01 |
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