反应详情

Sodium borohydride (0.26 g) was added to a solution of 6-isopropylazulene-2-carboaldehyde (1.4 g) in methanol (30 ml) at 0° C. and the mixture was stirred for one hour. Acetone was added to the reaction mixture and the mixture was stirred for 15 minutes. The reaction mixture was concentrated. The residue was purified by silica gel column chromatography (n-hexane-ethyl acetate) to obtain (6-isopropylazulen-2-yl)methanol (1.15 g).

1. stirringthe mixture was stirred for 15 minutes
2. concentrationThe reaction mixture was concentrated
3. customThe residue was purified by silica gel column chromatography (n-hexane-ethyl acetate)