HCID 58786609, compound → HCID 58786639, compound

Participants

Reaction Steps

A solution of product from Step I (750 mg, 2.44 mmol) in THF (15 mL) and isobutylmagnesium bromide (6.1 mL, 12.2 mmol, 2 M in THF) was heated at 70° C. for 24 h. The reaction was quenched with EtOAc and washed with brine, dried (Na2SO4), and evaporated. Final purification by flash chromatography (hexane-EtOAc 25:1) afforded,406 mg of the title compound. MS m/z 339.3 (M++1).

Provenance & Evidence