Hydrogen chloride-ethyl acetate → HCID 69431951, compound

HRID 1376064Notes

Reaction equation

HRID 1376064 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([CH:14]([CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[CH2:15][CH:16]([CH3:18])[CH3:17])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:25].CCOC(C)=O>>[ClH:25].[ClH:25].[CH:19]1([CH:14]([N:11]2[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]2)[CH2:15][CH:16]([CH3:18])[CH3:17])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 58786639HCID 58786639, compound

Product 1

HCID 69431951HCID 69431951, compound

Procedure

A solution of the product from Step II (406 mg, 1.21 mmol) in 1N HCl/EtOAc (25 mL) was stirred at room temperature overnight. Solvent was removed under reduced pressure and solid washed twice with Et2O to afford the title compound as a white solid. MS m/z 239.3 (M++1).

Workup

  1. customSolvent was removed under reduced pressure and solid
  2. washwashed twice with Et2O

Sources & evidence

ORD record
ord-9463dcf107c24db7bad0846f1a023dae
Source dataset
uspto-grants-2007_01
Patent number
US07169777B2

Reaction notes

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