Hydrogen chloride-ethyl acetate → HCID 69429143, compound

HRID 1376069Notes

Reaction equation

HRID 1376069 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([CH:14]([CH:25]2[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]2)[CH2:15][N:16]([CH2:21][CH:22]([CH3:24])[CH3:23])[S:17]([CH3:20])(=[O:19])=[O:18])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:31].CCOC(C)=O>>[ClH:31].[ClH:31].[CH:25]1([CH:14]([N:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)[CH2:15][N:16]([CH2:21][CH:22]([CH3:24])[CH3:23])[S:17]([CH3:20])(=[O:18])=[O:19])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]1

Participants

3

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 58786455HCID 58786455, compound

Product 1

HCID 69429143HCID 69429143, compound

Procedure

A solution of the product from Step III (446 mg, 1.22 mmol) in 1N HCl/EtOAc (25 mL) was stirred at room temperature overnight. Solvent was removed under reduced pressure and solid washed twice with Et2O to afford the title compound as a white solid. MS m/z 346.3 (M++1).

Workup

  1. customSolvent was removed under reduced pressure and solid
  2. washwashed twice with Et2O

Sources & evidence

ORD record
ord-32a3df36b0f84d56a00aea54b9717d67
Source dataset
uspto-grants-2007_01
Patent number
US07169777B2

Reaction notes

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