Hydrazine hydrate (1:1) → HCID 178503311, compound

Participants

Reaction Conditions

Reaction Steps

g (0.0061 mol) of 2'-nitro-3'-chloro-2-(methylthio)acetophenone are dissolved in 1.6 ml (0.012 mol) of N,N-dimethylformamide dimethyl acetal according to the procedure described in Example No. 1 and are heated at 70° C. and then, after isolation of the intermediate enaminone, are treated with 2 ml (0.042 mol) of hydrazine hydrate according to the procedure described in Example No. 1. After purification by passing through a silica column (heptane/ethyl acetate 75/25), 600 mg of the desired compound are obtained:

Provenance & Evidence