Sodium Hydroxide → HCID 22916430, compound

HRID 1376335Notes

Reaction equation

C([O:3][C:4]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]1[C:16]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:15]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[N:14]=[C:13]1[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)=[O:5])C.[OH-].[Na+]>>[C:4]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]1[C:16]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[C:15]([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)[N:14]=[C:13]1[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)([OH:5])=[O:3]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 22916382HCID 22916382, compound

Product 1

HCID 22916430HCID 22916430, compound

Procedure

Reaction of 1-(6-ethoxycarbonylhexyl)-2,4,5-triphenylimidazole (0.4 g) with sodium hydroxide in a method similar to Example 10 gave, after recrystallisations from ethanol and isopropanol, 1-(6-carboxyhexyl)-2,4,5-triphenylimidazole (0.19 g, 51%) as a white solid, m.p. 149°-150°; Found: C, 79.34; H, 6.65; N, 6.48%; C28H28N2O2 requires: C, 79.22; H, 6.65; N, 6.60%.

Workup

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customafter recrystallisations from ethanol and isopropanol, 1-(6-carboxyhexyl)-2,4,5-triphenylimidazole (0.19 g, 51%) as a white solid, m.p. 149°-150°

Sources & evidence

ORD record: ord-e735aacd7b5f4518bfe98bb779044cb1
Source dataset: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05663053

Reaction notes

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