Sodium Hydroxide → HCID 11726166, compound

HRID 1376344Notes

Reaction equation

HRID 1376344 reaction equation
[C:1]1([C:7]2[N:8]=[CH:9][N:10]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]([O:27]CC)=[O:26])[C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+]>>[C:1]1([C:7]2[N:8]=[CH:9][N:10]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]([OH:27])=[O:26])[C:11]=2[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 22916357HCID 22916357, compound

Product 1

HCID 11726166HCID 11726166, compoundYield 20%

Procedure

Ethyl 8-(4,5-diphenylimidazole-1-yl)octanate (3.25 g) was treated with sodium hydroxide as described in example 10 to give 8-(4,5-diphenyl-imidazol-1-yl)octanoic acid (0.6 g, 20%) as colourless needles, m.p. 129.5°-130° C.

Sources & evidence

ORD record
ord-66c51643bcb14cb986af94c33654efcb
Source dataset
uspto-grants-1997_09
Patent number
US05663053

Reaction notes

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